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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf8c424f32b8ec96abf016a670faee993ca3d5e35ece137d30e3776a1647c38d' 
  AND token = 'zsaYxAR6ueM/lF0tDTEM1u6XpajIob+TR2kxNQb448k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}