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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be9b3284ff6beab104b8a7bf735cc1f35900e36ff415d74f8639bb279c664569' 
  AND token = 'sSy4eQ02gv9pnlCTtOOspi9nmCuqDA/MkdsUIlUpvp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}