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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ce4b83cbe7182f897f939cbd12e1ebf5c17ec3a1355006bb464818cc042d47b' 
  AND token = 'VIT0GMtq6/V/kYXrEHi6bQeP5iIqdUhafz7Gp+pu9n0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}