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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1004defd275e8def103715327a9db834c2446830449e51b1b050bac2b0ef58d' 
  AND token = 'V3Pz+9DGQmP5C0pORRJzwI4h5Me++GO3EHMrDa0LK2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}