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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b002fa8fd21faa4795b7b40dc89c5fb72a02ffe8509051ca2042eb8b3fcaab8' 
  AND token = 'sOO59IkMg1WR/Xl0SBjn7V3Nnl+siFbbRREotlx+PnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}