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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '845cc5f2e4d8c13de3a7b9cdd1b3b38c9656259a321f3931a06850f4d344b2a9' 
  AND token = 'qzc59iRdG4RMRqKoAoVd1e3B9bm5Igg3zjO2Y3mL0EA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}