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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35389765a4590e1b32c7a9584705da16c8fd4cea7c003e600c9cd8fba9040331' 
  AND token = 'NdAnSpUrLPd7pyFYJuYaJU/ZRqFqXrQMPi90NmpOHYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}