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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22cb72994fd73c2e248099e48c38d3c3a1a415ecd57e295e25c362fcd3788ce1' 
  AND token = 'ucBZ8pw9pxiF/QhvDwtR5HNjbAeDOWbte9mgRoN/XcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}