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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78e2899434e9ce1ed43d12ed2118c89b88510387ed761e536c140e36c85643dd' 
  AND token = 'jbjoTuFTUCIQr1SgSCl+HuBDN+6rB1p7pT8bsHPRu0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}