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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21b3252cf344d96f512999aa207e09fc981e43954c7b4be2eef5ed29b2a4396a' 
  AND token = '/SOHdhBCLBmh5CJH1psVLvBnvucQ4bXb7taev5N0BN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}