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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69273d0361b7abe5e7c784430362f270ec58416e2068e5696d7d1de1f58279ec' 
  AND token = 'uN1e2DgWQfJ+cr0O3tAAIbXWivzBIoL6AHwQWL63a5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}