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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e432901571bd3f1f83cc813ffced5b23317730d2694b6f67727d2180485a3e1' 
  AND token = 'O6lrWE+ROE46rOpIjeeVWuwQCM9BrY/ygy+2/VNheqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}