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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6627bd670f48350f3d8af6f8a77f546220e5163468ec7312c41643a286ac43a' 
  AND token = 'X+oiU+eQEJ6VzsjR8FWwFz5bB3mBUuPi5P6V21pXnpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}