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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff0e8819da8b8b2101a044fcb328b657c0872d729c3e1fb3eac53c9fb88df5d3' 
  AND token = 'hN9QMZlf78VL1UlBpburzIvcLT3nZa1NV6iCqmUZeQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}