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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '606e2f13f3cc1f4b3a08703d6a627cd6a371d606f0b7ac1c6f67747a2f3235a9' 
  AND token = 'pfEww2edmzaQBMOi1hqeT5cHWbbLs0SregjSAsa8ucw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}