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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29ca3056c7bfd39f5696dac26e25b45b273eb9c10c50afbd305cc69ea36f9faa' 
  AND token = 'vQHsDGizwyxEvyZ3aCi9CI+hfJRNgsjkVOjTnvk/hY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}