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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a713fc9ba86d5585e49a3f7fe9ee1c342f2208f6055fa50748cbab6dd46dd33' 
  AND token = 'juOyO1D1iEEHXdewfOVzMWrw4n3xNB+g1M/D0MgWEnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}