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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e52109ea1f2eaf0ab387e50d328e9337d88ff021101fb64db627937f8a20bcc' 
  AND token = 'wF0NJIQwli/mDWsSIxtYhp4bmRvsvsdpK4GDq52D05Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}