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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b2878d3f2e15ac0b55f8b8ce802781c650be26d1f7d68df1bbaab7f69bff827' 
  AND token = 'kXZuFHoikUtWk58DGmMAoVQVor0UP6+2hGGwmO/xI3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}