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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a5ed69c41e4b71fa84326596d02526642cd7b1b335a95a3b0eed8240411e847' 
  AND token = 'uiQvbL5E2wNWyS/4LUric3sai72/edmjzluou98YbSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}