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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ffad233702811a6685b32039a51c0978e1e38c6dcbaf25daf8d02752a4fa005' 
  AND token = 'd19Z7xqm18cCx5fEnTmx3jD3zLOjp7tG3GMPhvypg5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}