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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f0928b55687c302921c6f81d57f5613702085c073974cbe784128e0f2dc3c25' 
  AND token = 'rcq3EURPex32SvSrOKKr+wvNUwa4ikDOr2vRQB+LuSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}