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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77cdf8f761732fb27fe6419009468d680017c6048c19e81bc124de142e2c800d' 
  AND token = 'GPFifzPL3wyrleE7oOXuNVla51Ios1cKBi610f5k468=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}