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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f00c2f9598c89d3c9e59dd40834e827b8b6f717401e8d11af5517158b00a661' 
  AND token = 'AXt3xaoDHdn1gn4Ta9wvORIV+/kLR9D4YvLF593ysiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}