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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6742d4d46bae35a77584b5a9bd282dd33ba23a8982e740629a75bc057882207' 
  AND token = 'Kfvmvspl23Js6apICbT7fG8P1VJ1Zjg+P4sxmargiVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}