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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '998a0377a87e0e1ef4e4121cc67cc749e2c60aa4c8494af700e040f26a27e7b5' 
  AND token = 'IZnYbiIQ8HYTEM2q/ygsgwS5rEXnN+RmD9MSCmvS2w4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}