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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2f3fc96f092d6d24714403dd413af263b2b2f01aeb11c3aa15f68d21839d3ef' 
  AND token = 'GNY8I04Yta45+sS6QcdWq/R37FSGgDB7UqAieK/7AcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}