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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adb06cd350f822431ded830a1513385c07b734db67c2a32e14b5e58d32c7f981' 
  AND token = 'Au7GGUPlWd/iRiI+AW28J4nMA4j8/ZSnpheBOkyGVaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}