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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c30d2d6e77af49cd2fb8552918588728e4f76d7672a1c9c949c0b6af0cba0c9' 
  AND token = 'MsIOMxbKO/onWIh5/7Zb5JK7eoZEZ8A18ZbKs6dvZlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}