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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4416dc8ed62c7b4f0387fc81bd40bc1c8327ce221a8bc7880690fc421f66698e' 
  AND token = 'newk5YsC7jnYTYKzh7XF1LKPWfiaAJNpDnPHHzYzGUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}