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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be55902e59e0542031f5f78eb4ead336449674d2b9c2648b69c4848e6f984e35' 
  AND token = 'DsTbJ3ioCcXLyrglz9+2jax9sD4eTK+EQqw9G5ELeF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}