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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24b57fa6c98e07c2166b6f2ca5e72657ed59d65c24d9587d135198e209e0b078' 
  AND token = 'O3NQ8F0RUhRwKb5+aNEwJY6alUfo17GCDi7GtBBIB4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}