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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '441a60f5e91c24ff28c71a0cbc8116e820c3d1eb4fe437445f8f9ed14b9c0368' 
  AND token = 'v3iBGTEjMnJUaEQQrR8A6K8ZUvJ2h/0JYxZeRDbWl+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}