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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46ad9fddba963c30620ad0d367022dea5995674da9a856e1e55aa79f17da4129' 
  AND token = 'EWTpwyndfBNb6S9XZVRiUhVq4w9cfpfy2Vv3ziRrAU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}