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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19c65ebaa31e8de3afe70dc10d7ca4344432d703e25035be8f4338a22c6e08ed' 
  AND token = 'CVQssiX+brc72A13IsWMhYj3BE/uGbRNx0U9vCjUvQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}