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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79e736dd66ce652dd84f21ad67f91a19df9b4e9d891b4060d2203bfb7be5f1f5' 
  AND token = 'MPLXBZJiOKcBiMhtc/g6uZBP4PmpEhIkiRBtPmY9pt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}