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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '678ce201795a11985b83fa2f4a745127146b7f26807b85ce6fcd03534dc83288' 
  AND token = '7Rn+TCb7TQEJLmQTJM02VnhYfELo2wE37CPx/9n9vN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}