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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b6d1af68b549b5e331c14cba4803a11a650ddb4cb88cdf29a43e97f3326befb' 
  AND token = '3zekf+1njRv+Itm1O41FgbhxMdfOt4dOkh46Gitg3S4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}