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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0be0f0058b998a00ed5230099f1b5096636a085e6c14f1f007543b41196d427f' 
  AND token = 'vGJpTGVwpwwV2+VbRt+Si9F+6KUEnB4oqP5WWiV6DL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}