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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6862d6eb865dd5c6f65006de36a770af5bea3677d1c16635bdeea5b18bb221b9' 
  AND token = 'tIDwx6vluXORssUp7QA7HY8WTF1VzGoyaCNmHffhFxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}