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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bc7acb534e0600102636c1ca66d160f01b05b6b570f8cc780cbbd54d79d3c7a' 
  AND token = 'uxOI57JeO9L4V6YmmLiZoADPbewozjTj+c9PubKpAtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}