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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ea55caa322a081add2d1008bdf9ce5273b5b370a6585900517425773e085622' 
  AND token = 'TNcfm5fMhYWQIQUZhd09ONpVPcYLrg9nxrNQFnku4uE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}