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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '222aef27bc3edcb0ebe4066458dc511c592834caf7f9bd35a1b20fe9fa7ce196' 
  AND token = 'FsAn4pVoF4hc8rHFgmBKl52wOpBE2dS7Vf4I7bRdfsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}