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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44c8538a8b5490f254088d79ee89c9c496fe911539d2300716d07b6c201cf509' 
  AND token = 'MzHvuoU+Esyg+6K+QNlZ/FaEleSz+EkY80HrYoKTzYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}