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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ca9f328b7bf38259d4d475b772ff02f1691c868422706c6d8c186bbca105aca' 
  AND token = '6YCTl/J5dREMN1ap8a359LLDqqrXsWhE5vd2/9ZZ9us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}