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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e7c5512cbdd521d4ece2d80224ebfa4bf2ad0d69db5961a53cc168a096b4b50' 
  AND token = 'SQCT7cBmpFKrtREu7zSTpvDK5ufcbNNF9qM9NPtcPmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}