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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '949efc6cd6dc4206844d44b9a2889d3d1b355fc8a1661378e091614378ca7331' 
  AND token = 'TnUOlQ6U77EPDEPWl6/VH1cwj1IF568RcFNUZ74C1G4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}