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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e9a567d804002a514a5c8708146519a97008cb0b90a66244f3c345ad6bfbe7b' 
  AND token = 'z37PfTfmUaslQr0yalagPyO9KJKrw2zPDg5lzIO9JYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}