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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48a48da3a1de5d85cc1f884387be6e44ea54382732cc8876405140eee63629d6' 
  AND token = 'J6Jq+bgcYFtll9Ki/2N2XKkZJICkl19DDpt9YWx0i7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}