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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '305b5bdea3428dcf7590c14e0c921ebff812da4fb01323cf4e730fc5a52bdaf3' 
  AND token = 'bkb1X9Z4tqW+9J19QU7vn4Fy8/mMI+Wzghu4KltjqNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}